Raise your hands if you want to age quickly, I don’t think I’ll see any hands even dislodging from their current position. But do we know what causes ageing? Oxidative stress, glycation, telomere shortening, and chronological age — along with various genes — are some of the causes that work together to cause ageing. I know most of us either would have bunked or wouldn’t have paid attention during our science classes. I’ll try to explain one of the causes and in return, you can reduce anteing up on anti-ageing creams!
In order to grow and age, our bodies must duplicate their cells. Mitosis is a process that allows one parent cell to divide into two new daughter cells. During mitosis, cells make copies of their genetic material. Half of the genetic material goes to each new daughter cell. To make sure that information is successfully passed from one generation to the next and not lost during duplication, each chromosome has a special protective cap called Telomeres. These are like the plastic tips or aglets on shoelaces, according to one analogy. Every time your cells replicate, they lose a bit of this protective cap. Before a cell can divide, it makes copies of its chromosomes so that both new cells will have identical genetic material. To be copied, a chromosome's two DNA strands must unwind and separate. It begins the process with the help of short pieces of RNA. When each new matching strand is complete, it is a bit shorter than the original strand because of the room needed at the end for this small piece of RNA. It is like someone who paints himself into a corner and cannot paint the corner. When they get too short, the cell can no longer divide; it becomes inactive or senescent or it dies. This shortening process is associated with ageing.
But the shrinkage is faster in some people than in others, explains study author Larry Tucker, professor of exercise science at Brigham Young University. Conversely. “Just because you’re 40, doesn’t mean you’re 40 years old biologically,” he says in a statement. “We all know people that seem younger than their actual age. The more physically active we are, the less biological ageing takes place in our bodies.”
In the study, exercise science Tucker compared telomere length with levels of physical activity. The study, published in the medical journal Preventive Medicine, finds that people who have consistently high levels of physical activity have significantly longer telomeres than those who have sedentary lifestyles, as well as those who are moderately active. Based on the study, Tucker marks the threshold at around 30 minutes of jogging five days a week for women and 40 minutes five days a week for men.
Geneticist Richard Cawthon and colleagues at the University of Utah found shorter telomeres are associated with shorter lives. Among people older than 60, those with shorter telomeres were three times more likely to die from heart diseases and eight times more likely to die from infectious diseases. When healthy individuals perform a cardiovascular workout, their muscles increase transcription of telomeres, according to a study published in Science Advances.
About The Author: Director - Fitness Division at RESET - Holistic Living Concepts.